Molnupiravir When Used Alone Seems to Be Safe and Effective as Outpatient COVID-19 Therapy for Hemodialyzed Patients and Kidney Transplant RecipientsArticle Published on 2022-10-092022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] Acute kidney injury antiviral activity automated Comorbidity concerning cough COVID-19 COVID-19 therapy demonstrated diagnosed with COVID-19 dose Efficacy ESKD ESRD Fever Hemodialysis Immunosuppressive medication in vitro Interaction joint kidney Kidney disease kidney transplant kidney transplant recipient kidney transplant recipients Kidney transplantation knowledge molnupiravir molnupiravir. Nasopharyngeal swab specimens nucleic acid amplification Observational cohort study Outpatient Pain Patient performed Poland positive-sense recipient resolved retrospective RNA viruses SARS-CoV-2 SARS-COV-2 infection serum creatinine Side effect therapy Transplant Treatment weakness [DOI] 10.3390/v14102224 PMC 바로가기
Diagnostic Performance Assessment of Saliva RT-PCR and Nasopharyngeal Antigen for the Detection of SARS-CoV-2 in PeruArticle Published on 2022-08-312022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] analyzed Antigen assessment asymptomatic individual calculated Care community transmission COVID-19 COVID-19 pandemic cycle threshold Cycle threshold value detection Diagnosis diagnostic enrolled Frequency Health nasopharyngeal Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens nasopharynx noninvasive technique North participant performance performed Peru Predictive public health pulse oximetry reference standard reverse transcription PCR RT-PCR RT-PCR diagnosis Saliva SARS-CoV-2 Screening SD Biosensor seeking sensitivity Sensitivity and specificity specificity Symptom symptom onset symptomatic individuals threshold validation study Validation. Viral load [DOI] 10.1128/spectrum.00861-22 PMC 바로가기
Indiscriminate SARS-CoV-2 multivariant detection using magnetic nanoparticle-based electrochemical immunosensing자성 나노입자 기반 전기화학적 면역 센싱을 이용한 무차별 SARS-CoV-2 다변량 검출Article Published on 2022-06-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accuracy Alpha Anti-S1 anti-S2 anti-SARS-CoV-2 antibody antibody cocktail antigen test calibration delta variant Delta variants demonstrated Developing diagnose Diagnosis diagnostic Efficiency electrochemical biosensor Frequency include Indiscriminate infected patient infected patients limit of detection Magnetic nanoparticles mitigate monoclonal monoclonal antibodies monoclonal antibody Mutation nasopharyngeal Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab specimens nasopharyngeal swabs optimization pandemic performed platform polyclonal polyclonal antibody positive positive sample RT-PCR SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 virus SARS-CoV-2. sensitivity specificity Swab tested the SARS-CoV-2 virus variant variants variants of SARS-CoV-2 [DOI] 10.1016/j.talanta.2022.123356 PMC 바로가기 [Article Type] Article
Matrix-Assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry Analysis for the Direct Detection of SARS-CoV-2 in Nasopharyngeal Swabs비인두 면봉에서 SARS-CoV-2의 직접 검출을 위한 매트릭스 보조 레이저 탈착 및 이온화 비행 시간 질량 분석 분석Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid anion exchange resin biological molecule biological molecules cartridge Chain Reaction Combination complex contagious coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patients detect detection Diagnostic method digested Direct Evidence flight identify in some inoculated ionization labor-intensive Laser limit of detection mass mass spectrometry Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens nasopharyngeal swabs nucleocapsid patients PCR peptide peptides polymerase chain polymerase chain reaction positive result purification purified Real-Time Reverse Transcription Polymerase Chain Reaction reverse transcription reverse transcription polymerase chain reaction SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral particle SARS-CoV-2 viral particles SARS-CoV-2-specific peptide SARS-CoV-2-specific peptides selected separated Seven severe acute respiratory syndrome Coronavirus specimen specimens Spectrometry Swab the SARS-CoV-2 trypsin Viral load was performed [DOI] 10.1021/acs.analchem.1c04328 PMC 바로가기 [Article Type] Article
Highly sensitive and ultra-rapid antigen-based detection of SARS-CoV-2 using nanomechanical sensor platform나노기계 센서 플랫폼을 이용한 SARS-CoV-2의 고감도 및 초고속 항원 기반 검출Article Published on 2022-01-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 변종, 치료기술, 치료법, 치료제, [키워드] analytical sensitivity antibody Antigen antigen detection antigenic protein antigenic proteins antigens clinically Concentration demonstrated detection develop extreme Interaction less Microcantilever Microscopy mutants N protein Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens optical Pathologies pathology Patient platform Protein qRT-PCR Rapid RBD Real-time monitoring Receptor binding domain SARS-CoV-2 SARS-CoV-2 nucleocapsid sensitivity sensor sensor. Signal transduction specificity spread of COVID-19 Swab variant [DOI] 10.1016/j.bios.2021.113647 PMC 바로가기 [Article Type] Article
Nasopharyngeal Expression of Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 in Children within SARS-CoV-2-Infected Family ClustersSARS-CoV-2에 감염된 가족 클러스터 내의 어린이에서 Angiotensin-Converting Enzyme 2 및 Transmembrane Serine Protease 2의 비인두 발현Research Article Published on 2021-11-032022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 유전자 메커니즘, [키워드] ACE2 ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Adults age age and sex Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 association children confidence interval contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 differential expression Evidence expression Families family family member family members groups Hypothesis incidence Infection laboratory-confirmed SARS-CoV-2 infection Lower Multivariate analysis nasal nasal epithelium nasopharyngeal Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nasopharyngeal swab specimen Nasopharyngeal swab specimens negative patients not significantly different Odds ratio Patient pediatric populations positive recent respiratory SARS-CoV-2 SARS-CoV-2 entry factors SARS-COV-2 infection Serine severe acute respiratory syndrome Coronavirus significantly significantly higher Support TMPRSS2 transcript level transcript levels transmembrane serine protease transmembrane serine protease 2 [DOI] 10.1128/Spectrum.00783-21 PMC 바로가기 [Article Type] Research Article
Self-Collected Oral Fluid and Nasal Swabs Demonstrate Comparable Sensitivity to Clinician Collected Nasopharyngeal Swabs for Coronavirus Disease 2019 Detection자가 수집 구강액 및 비강 면봉은 코로나바이러스 질병 2019 검출을 위해 임상의가 수집한 비인두 면봉과 유사한 감도를 나타냄Article Published on 2021-11-022022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 clinician coronavirus COVID19 detect detection nasal nasal swab Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens oral Participants performed pharyngeal pharyngeal. positive SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus specimen specimens swab specimen [DOI] 10.1093/cid/ciaa1589 PMC 바로가기 [Article Type] Article
Time-course evaluation of the quantitative antigen test for severe acute respiratory syndrome coronavirus 2: The potential contribution to alleviating isolation of COVID-19 patients중증급성호흡기증후군 코로나바이러스 2에 대한 정량적 항원 검사의 시간 경과 평가: COVID-19 환자 격리 완화에 잠재적 기여Observational Study Published on 2021-11-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 임상, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis Antigen automated Chain Reaction change characteristic conducted coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients cutoff point cutoff value detect determine diagnostic Diagnostic accuracy early stage examined facilitate indicated Infectivity infectivity assessment Inpatient Inpatients investigated Isolation late stage Lumipulse Mass screening Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens Negative predictive value observational study patients polymerase chain polymerase chain reaction Positive predictive value Predictive value Quantitative Quantitative antigen test receiver operating characteristic retrospective ROC ROC analysis SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2. scatterplot sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity specimen specimens stages was used [DOI] 10.1016/j.jiac.2021.08.015 PMC 바로가기 [Article Type] Observational Study
Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens비강 중비갑개 면봉 표본에서 항원 검출과 SARS-CoV-2 서브게놈 RNA의 상관관계Expedited Published on 2021-11-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen antigen detection coronavirus coronavirus disease COVID-19 detectable detection diagnostics identify nasal nasal midturbinate nasopharyngeal Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens nucleocapsid outpatients remained respiratory respiratory infections RNA SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 subgenomic RNA swab specimen swab specimens symptomatic virus replication viruses zoonoses [DOI] 10.3201/eid2711.211135 PMC 바로가기 [Article Type] Expedited
SARS-CoV-2 N gene mutations impact detection by clinical molecular diagnostics: reports in two cities in the United StatesSARS-CoV-2 N 유전자 돌연변이가 임상 분자 진단에 의한 검출에 영향을 미침: 미국의 두 도시에서 보고Article Published on 2021-11-012022-09-11 Journal: Diagnostic microbiology and infectious disease [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] analyzed Cepheid Cepheid XpertXpress COVID-19 diagnostic diagnostic testing molecular Mutation N gene nasal Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens New York City nucleotide Pittsburgh SARS-CoV-2 SARS-CoV-2 diagnostic testing SARS-CoV-2 N gene single nucleotide polymorphisms single nucleotide polymorphisms. tested the United State Viral viral genome whole-genome sequencing [DOI] 10.1016/j.diagmicrobio.2021.115468 PMC 바로가기 [Article Type] Article